Mourinho’s future has been the subject of intense scrutiny this season – and the club’s worst start to a season in 28 years was confirmed with defeat at Liverpool on Sunday.
The 55-year-old Portuguese insisted at Anfield that he had not lost the dressing room, as his team sat sixth in the Premier League table and 11 points off the Champions League places.
But Manchester United announced on Tuesday that “manager Jose Mourinho has left the club with immediate effect”.
A statement continued: “The club would like to thank Jose for his work during his time at Manchester United and to wish him success in the future.
Fractures in his relationship with Paul Pogba began to emerge in September and the France World Cup winner was stripped of the vice-captaincy before Sky Sports
Pogba was left on the bench for the game against rivals Liverpool on Sunday along with other star players such as Anthony Martial, whose ongoing contract dispute with the club has only added to the inner turmoil at Old Trafford.